Lionel Messi's three goals lifted Argentina into the World Cup on the last day of South American qualifying, keeping the Albiceleste from missing out for the first time since 1970.
The two-time champions - and losing finalists three years ago in Brazil - rode Messi's hat trick in the thin air of the Andes and rallied for a 3-1 win over Ecuador, which took a surprising lead in the first minute.
"I told the group that Messi does not owe Argentina a World Cup, but rather football owes the world to him," Argentine coach Jorge Sampaoli said. "Argentina took a step forward, and in time we can be competitive."
The top four teams in South America get automatic berths to Russia. Brazil has 41 points and clinched months ago. The other three advancing Tuesday went in this order: Uruguay (31), Argentina (28) and Colombia (27).
Uruguay beat Bolivia 4-2, Argentina won 3-1, Colombia drew 1-1 with Peru and last-place Venezuela beat Paraguay 1-0.
Peru (26) placed fifth and will keep alive its bid for a first World Cup appearance since 1982 after edging Chile for the South American spot in the inter-continental playoff next month against Oceania representative New Zealand.
On a dramatic last day of continental qualifying tournaments, six South American teams - separated by only four points over 17 matches - had shots at the World Cup entering play.
Chile and Paraguay missed out at the last moment. Venezuela, Bolivia and Ecuador were already out of contention.
Chile lost 3-0 to Brazil, the 12th straight unbeaten qualifying game for Brazil coach Tite.
There was a major shock in CONCACAF qualifying for teams in North and Central America and the Caribbean, with the U.S. slipping from third spot to fifth with a loss in Trinidad and missing out on the World Cup.
It looked easy for Argentina. But it wasn't, particularly after Romario Ibarra gave Ecuador a 1-0 lead in the first minute at 2,850 meters (9,350 feet) in Ecuador's capital.
"Even with a goal against us you could see the certainty of a team that knew how to play the game," Sampaoli said.
Messi scored off a pass from Angel di Maria in the 12th, left-footing home from close range. In the 20th, Di Maria slipped a pass through to Messi, who drove the ball into the top corner from 15 yards.
Messi got his third in the 62nd, weighting a perfect 18-yard shot that went in just over the fingers of Ecuador keeper Maximo Banguera.
"I won't make any promises," said Sampaoli, the third coach in this qualifying cycle for Argentina, which lost 1-0 to Germany in the 2014 World Cup final.
Then he added: "The nationality of the best player in the world is luckily Argentine."
Colombia advanced with a 1-1 draw in Lima, Peru. The result also put Peru into a playoff in November with New Zealand for a spot in Russia.
James Rodriguez gave Colombia a 1-0 lead in the 56th, but Peru's Paolo Guerrero equalized in the 76th to give Peru a chance.
"We're fifth," so we get the playoff," Guerrero said. "We could have done a bit more, but the big thing we can think of is the playoff."
Two-time defending South American champion Chile needed to win to get its third straight World Cup berth. Brazil wrecked that with a 3-0 victory.
Gabriel Jesus scored twice and Paulinho got the other. It was the 12th consecutive undefeated qualifying game since Tite has been in charge. He took over more than a year ago from Dunga.
Uruguay was a cinch to advance. It did with style, beating Bolivia 4-2. Luis Suarez scored twice with other from Martin Caceres and Edinson Cavani.